Renal Biomarkers Emerging Tools for Early Kidney Disease Detection and Management
Serum Creatinine and eGFR
Serum creatinine has long been used to estimate GFR, but it is an indirect and unreliable marker until GFR has declined substantially. More accurate estimated GFR (eGFR) formulas have been developed based on creatinine, age, sex and race. However, eGFR also has limitations as a late-stage biomarker. Rising or abnormal creatinine may not occur until 40-50% of kidney...
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