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Olivopontocerebellar Atrophy (OPCA) is a rare syndrome which describes about neurodegenerative disorders. The conditions are characterized by disequilibrium, impairment or inability to coordinate voluntary movements (cerebellar ataxia), and difficulties in speech, termed as dysarthia. OPCA has been categorized based on clinical, genetic and neuropathological characteristics. OPCA can be hereditary or acquired.
Key Growth Drivers:
Olivopontocerebellar Atrophy (OPCA) is a rare syndrome which describes about neurodegenerative disorders. The conditions are characterized by disequilibrium, impairment or inability to coordinate voluntary movements (cerebellar ataxia), and difficulties in speech, termed as dysarthia. OPCA has been categorized based on clinical, genetic and neuropathological characteristics. OPCA can be hereditary or acquired.
The hereditary OPCA refers to a system of disorders whose conditions, overlay with spinocerebellar ataxia (SCA). The rare types of OPCA follow the autosomal recessive heritage which consists of the Fickler-Winkler type OPCA and the pontocerebellar hypoplasia conditions. The symptoms of OPCA very form person to person. The patients experience difficulty with gait of legs and arms. Other symptoms are difficulty in controlling bladder and bowels, hindrance in locomotory movement, loss of memory. The atrophy is caused due to the OPCA-X (SCA-X1) followed X-linked inheritance. The X-linked recessive genetic disorders are caused by an abnormality in the X chromosome gene, which occurs mostly in males. It affects the male and females in equal statistics. There is no specific therapy or treatment for individuals with OPCA. The patients undergo speech therapy, dopaminonergic conditions. Propranolol has been used to treat trauma associated with OPCA, with limited benefit. Baclofen is used for treatment for spasticity.
The report outlines the involvement of key players, including:
The major players covered in the Olivopontocerebellar Atrophy (OPCA) market are Pfizer Inc., AbbVie Inc., Merck & Co. Inc., Amneal Pharmaceuticals Inc., Teva Pharmaceutical Industries Ltd., C.H. Boehringer Sohn AG & Ko. KG, Novartis International AG, GlaxoSmithKline Plc., Biogen Inc., among other domestic and global players. DBMR analysts understand competitive strengths and provide competitive analysis for each competitor separately.
Key Market Segmentation
- On the basis of type, the olivopontocerebellar atrophy (OPCA) market is segmented into hereditary OPCA, sporadic OPCA.
- On the basis of gender, the olivopontocerebellar atrophy (OPCA) market is segmented into male and female.
- On the basis of drug class, the olivopontocerebellar atrophy (OPCA) market is segmented into dopaminergic agents, serotonin 5-hydroxytryptophan (5ht) 1-a receptor agonists, antihypertensive agents, antianxiety agent, interferons, decarboxylase inhibitors, immunomodulator, antidepressant.
- On the basis of indication, the olivopontocerebellar atrophy (OPCA) market is segmented into multiple sclerosis, Parkinson’s Disease, Alzheimer’s disease, spinal muscular atrophy (SMA) and others.
- On the basis of route of administration, the olivopontocerebellar atrophy (OPCA) market is segmented into oral, parenteral.
- On the basis of end user, the olivopontocerebellar atrophy (OPCA) market is segmented into hospitals, home care, specialty clinics.
- On the basis of distribution channel, the olivopontocerebellar atrophy (OPCA) market is segmented into hospital pharmacy, retail pharmacy, and online pharmacy.
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