Market Overview –

Aptamers market size is expected to reach USD 2.3 billion by 2022. The Aptamers market industry is expected to increase from USD 2.74 billion in 2023 to USD 11.42 billion in 2032, with a compound annual growth rate (CAGR) of 19.50% during the forecast period (2023-2032).

The Aptamers Market is expanding rapidly, driven by the increasing interest in aptamer therapeutics for various medical applications. Aptamers are single-stranded DNA or RNA molecules that bind to specific targets, offering potential advantages over traditional therapeutics. The market offers a range of aptamer-based drugs and diagnostics, promising innovative solutions for treating diseases and improving patient outcomes.

The aptamers market focuses on a class of molecules known as aptamers, which are short, single-stranded DNA or RNA sequences that bind to specific target molecules with high affinity and specificity. Aptamers are used in various applications, including diagnostics, therapeutics, drug delivery, and research tools.

Key Impacting Factors and Barriers

Aptamers are gaining widespread interest of scientists, as a multifunctional molecule that offers a number of benefits compared to the well-known antibodies. For instance, aptamers help reduce the period of time generally required for benchmark testing, saving close to 35% of the overall cost and numerous years of research and development (R&D) of these molecules. Other advantages include significant thermal stability, lower chance of triggering unnecessary immune responses, and cost effectives, which help bolster its demand and use. The aptamers market has been gaining strength across countries, with the increase in government support, mounting awareness among manufacturers, and potential pipelines.

A number of research activities over the years have revealed that the medication method or functional mechanism of the aptamer is quite similar to the antibodies. These studies have helped the market get the attention of a large number of investors. The number of firms that are striving to explore the application scope of the molecule across diverse medical areas has increased splendidly in the last few years, which also favors the market growth. Another key development can be the fast surge in the number of small sized enterprises and startups trying to capture the unleveraged growth potential of the aptamers industry. Companies like Aptamer Sciences, Inc., Aptamer Group and Aptagen LLC are some of the top players that are expected to face tough competition from the new entrants in the following years, giving a major push to the market growth.

Many of the key market contenders are concentrating on intensive R&D activities to come up with novel and advanced aptamers to cater to a broader range of medical use-cases. Big names in the pharmaceutical industry such as Merck & Co., Inc., Eli Lilly & Company, and more are spending generously on oligonucleotide therapy. Some of vendors are also collaborating with smaller manufacturers to bolster their market presence. To illustrate, in October 2020, Qualigen Therapeutics Inc. entered an agreement with the University of Louisville to accelerate the advancement of its study that focuses on an anticancer drug candidate AS1411-GNP, also known as Aptamer-Linked Anti-Nucleolin (ALAN). The primary objective of the study is to analyze the antitumor efficiency along with the safety aspect of various ALAN compositions for the treatment of adult and pediatric acute myeloid leukemia.

Market Segmentation

Aptamers industry can be segmented with respect to type, application, technology and end users.

The different types of aptamers available are peptide aptamers and nucleic acid aptamers. The various nucleic acid aptamer types are RNA-Based Aptamers and DNA-Based Aptamers.

The key application areas of aptamers are research and development, therapeutics development, diagnostics and more.

The technologies that have been considered in the MRFR study are X-aptamer, MARAS technique and Selex.

Some of the top market end users included in the report are contract research organizations, biotechnology and pharmaceutical companies, academic and government research institutes, and others.

Regional Study

The geographical distribution of the global Aptamers Market covers the Americas, Asia Pacific or APAC, MEA or Middle East and Africa and Europe.

America can be the highest revenue generating market in the upcoming years, as a result of the region’s tendency to fast adopt the latest and modern medical technologies and the knack for investing significantly in areas with high potential, such as aptamers. A few other growth boosters can be the soaring demand for aptamer therapeutics and the exploding pool of research laboratories. Experts believe that the food and beverage industry in America can emerge as one of the top end-users in the foreseeable future, in the wake of emerging use of aptamers as biosensors to ensure product quality.

APAC market could be another noteworthy contender in the ensuing years, thanks to the rising availability of well-equipped healthcare facilities and the mounting number of government initiatives. Uptake of advanced medical technologies and the increasing healthcare spending also favor the APAC market’s growth. With the rise in ambitious start-ups, escalating number of products that are undergoing clinical trials, and the growth of academic laboratories that are focusing on exploring the application scope of aptamers, APAC will be able to clinch a higher position in the global industry.

Key Players –

Aptamers companies include SomaLogic Operating Co., Inc., Aptamer Group Inc, Aptagen LLC, Aptamer Sciences Inc., Base Pair Biotechnologies Inc., Aptus Biotech SL, TriLink Biotechnologies, AstraZeneca, AM Biotechnologies, Aptadel Therapeutics, and Ophthotech Corporation.

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