The global preparative chromatography market was valued at US$ 1,311.8 million in 2023 and is expected to reach US$ 2,139.4 million by 2034. The market is set to expand at a CAGR of 4.5% over the forecast period. It is projected to attain a valuation of US$ 1,377.9 million by 2024.

The pharmaceutical and biotechnology industries' growing need for and approval of monoclonal antibodies is fueling the market's expansion. The market is also influenced by the growing necessity for sophisticated purification methods and the requirement for more productive & affordable procedures. Creating novel chromatography products and technological developments are anticipated to accelerate market expansion. 

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Future growth in the pharmaceutical and biotechnology sectors is anticipated to be substantial due to the increasing demand for and production of preparative chromatography. Materials for the production of the coronavirus vaccine were analyzed using preparative chromatography and the separation process.

The increasing need for omega-3 fatty acids & insulin, growing worries about food safety & quality, and an aging population are all contributing to the rise of the market. Furthermore, research in the market is anticipated to be driven by current paradigms that concentrate on analyzing and separating monoclonal antibodies employing moderate reverse-phase chromatography.

Key Takeaways from the Market Study:

  • The United States is expected to surge at a CAGR of 2.3% by 2034.
  • Germany is projected to rise at a 2.1% CAGR by 2034 based on country.
  • Based on the product, the detector segment is expected to rise at a CAGR of 8.1% by 2034.
  • By application, the pharmaceutical segment is projected to surge at 2.6% CAGR by 2034.
  • By 2024, the preparative chromatography market is set to reach US$ 1,377.9 million.

"Due to its great selectivity and scalability, preparative chromatography is essential for meeting the purity standards of components necessary for regulatory compliance. As the market for monoclonal antibodies and other biopharmaceuticals grows, preparative chromatography is becoming an increasingly important technology in the bioprocessing chain," opines Sabyasachi Ghosh Associate Vice President at Future Market Insights (FMI).

Competitive Landscape:

Leading manufacturers in the industry employ key strategies to enhance their market presence and product offerings through innovative products. A handful of instances indicating how market players expanded and achieved top positions through market expansion and the introduction of new and advanced products: 

  • In June 2022, Bio-Rad Laboratories, Inc. launched CHT™ prepacked Foresight Pro Columns, specifically designed to help downstream chromatography applications.
  • In 2021, CEM launched the Prodigy preparative high-performance liquid chromatography (HPLC) system.

Key Companies Profiled:

  • Thermo Fisher Scientific Inc.
  • Bio-Rad Laboratories, Inc.
  • Agilent Technologies, Inc.
  • Waters Corporation
  • Cytiva (Danaher)
  • Satorius AG
  • Shimazdu Corporation
  • PerkinElmer Inc.
  • Hitachi High-Tech Corporation
  • KNAUER Wissenschaftliche Geräte GmbH
  • Gilson Incorporated
  • JASCO Global
  • Jiangsu Hanbon Science&Technology Co., Ltd.
  • LPP Equipment AG
  • Teledyne ISCO
  • YMC CO., LTD.
  • ECOM spol. s r.o.
  • Sheng-Hanp.
  • Sykam GmbH
  • Postnova Analytics GmbH

Preparative Chromatography Market Segmentation by Category:

By Product:

  • Systems
    • Semi-preparative HPLC Systems
    • Preparative HPLC Systems
  • Resins
    • Affinity Chromatography (AC)
    • Ion exchange Chromatography (IEX)
    • Size-exclusion Resins
    • Hydrophobic Interaction Resins
    • Mixed-mode/Multi-mode Resins
    • Other Resins
  • Detectors
    • UV/Vis Detectors
    • Diode-array Detectors
    • Refractive Index Detectors
    • Fluorescence Detectors
    • Mass Spectrometry Detectors
    • Evaporating Light Scattering Detectors
    • Electrochemical Detectors
  • Consumables
  • Columns
    • Prepacked Columns
    • Empty Columns

By Application:

  • Pharmaceuticals
    • Small Molecule
    • Peptides
    • Oligonucleotides
    • Monoclonal Antibodies
    • Others
  • Cosmetics
  • Food Ingredients
  • Molecular Biology and Diagnostics
  • Fine Chemical and Synthetic Chemistry
  • Environmental Chemistry
  • Forensic Sciences
  • Drugs of Abuse and Sports Drug Testing
  • Research Use
  • Other Application

By End User:

  • Pharmaceutical Companies
  • Biotechnology Companies
  • Contract Research Organizations
  • Cosmetic Manufacturers
  • Food and Beverage Industry
  • Chemical Industry
  • Diagnostic Laboratories
  • Reference Laboratories
  • National Anti-doping Organizations
  • Law-enforcement Agencies
  • Academic and Research Institutes

By Region:

  • North America
  • Latin America
  • East Asia
  • South Asia and Pacific
  • Western Europe
  • Eastern Europe
  • Middle East and Africa