Global Acellular Skin Substitutes Market: Overview

Tissue engineered skin substitutes or artificial skin substitutes can be defined as bioengineered skin substitutes derived from human tissue, non-human tissue, synthetic materials, and composite of these materials. These are mostly used in the treatment of burns, diabetic ulcers, vascular ulcers, and lacerations. Acellular skin substitutes are collagen-rich matrices prepared by removing the cellular components (protein and collagen matrix) of human cadaver skin.

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Rise in preference for acellular skin substitutes for implant-based skin surgery accelerates the growth of the global acellular skin substitutes market. The American Society of Plastic Surgeons (2012) stated that more than 50% surgeons in the U.S. preferred acellular matrix for skin surgeries. Moreover, rapid rise in the incidence rate of skin disorders across the globe is likely lead to an increased number of patients who will undergo either invasive or non-invasive skin surgeries. According to the American Academy of Dermatology (2013), one in five persons in the U.S. is expected to develop skin disorder in his/her lifetime.

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Global Acellular Skin Substitutes Market: Drivers and Restraints

Acellular skin substitutes are widely utilized for most of the chronic skin disorders across the globe. Hence, rapidly increasing skin disorders is expected to boost global demand for acellular skin substitutes. Availability of up-to-date treatment facilities, skilled doctors and consultants, low cost of treatments in countries such as India, Thailand, Malaysia, and Singapore propel the medical tourism industry. This in turn results in the growth of the global acellular skin substitutes market. Currently available skin surgeries are mostly invasive and require extended healing time and treatment cost. New products and services present large opportunities as the market consists of established players and their brands, but lacks minimally invasive skin surgeries and highly efficient products. Safety and efficacy are the major concerns in the acellular skin substitutes market. Hence, introduction of new products offer an opportunity to enter and establish business in the market. Therefore, focus on low cost and minimally invasive acellular skin substitutes products and procedures is likely to help manufacturers to record high growth in revenue and market share.

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Global Acellular Skin Substitutes Market: Key Segments

The global acellular skin substitutes market can be segmented based on source of cells, application, and region. In terms of source of cells, the global market can be categorized into animal and human. Products derived from animal sources are developed by harvesting living tissue from various donor animals such as bovine, equine, and porcine. Products derived from animal cells include Unite BioMatrix Collagen Wound Dressing, Synovis, and INTEGRA. Allografts are products derived from human cadaver skin. Products derived from human cells include AlloDerm and GraftJacket. Based on application, the global acellular skin substitutes market can be divided into diabetic foot ulcers, lower extremity venous ulcers, ulcers of mixed etiology, pressure ulcers, and plastic surgeries. Appropriate treatment using acellular matrix in various skin diseases results in faster healing.

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Geographically, the global acellular skin substitutes market can be segmented into five major regions: North America, Europe, Asia Pacific, Latin America, and Rest of the World. North America holds the largest share of the global acellular skin substitutes market, followed by Europe. The dominance of these two regions is attributed to increase in prevalence of vascular diseases and rise in demand for skin substitutes. The regions are likely to continue to dominate the global acellular skin substitutes market during the forecast period due to rise in number of injuries and increase in awareness among people. Aging population is a major concern in Europe. The geriatric population is more prone to venous diseases due to reduced immunity and longer stay in hospitals since the wound healing process is slow in elderly people. The European Commission (Eurostat) has estimated that the geriatric population in Europe is expected to reach 525 million by 2035. Hence, rise in the geriatric population is projected to boost demand for acellular skin substitutes in Europe.

Global Acellular Skin Substitutes Market: Key Players

Key players in the global acellular skin substitutes market include Acelity L.P., Inc., Integra LifeSciences Corporation, and Smith & Nephew plc.

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