The extraction, purification, and refinement of important bioproducts are crucial tasks for the downstream processing market in the dynamic fields of industrial biotechnology and biopharmaceuticals. This crucial but frequently skipped phase makes ensuring that biopharmaceuticals, enzymes, biofuels, and other biotechnological goods are as effective and high-quality as possible when they are delivered to consumers. Downstream processing is positioned to experience tremendous growth and innovation as the biotech sector continues its fast expansion.

Downstream processing involves a series of sophisticated techniques designed to isolate and purify desired biomolecules from complex mixtures obtained during fermentation or cell culture processes. The process encompasses numerous purification steps, including separation, filtration, chromatography, and drying, among others. Through these steps, impurities are removed, and the desired biomolecules are concentrated to achieve the desired quality and potency.

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By the end of 2032, the market for downstream processing is expected to be worth US$ 72.3 billion, growing at a CAGR of 11.3% between 2022 and 2032. The size of the worldwide downstream processing market was estimated at US$ 22.0 billion in 2021, and by the end of 2022, it is predicted to reach US$ 24.9 billion.

Several factors are driving the growth of the downstream processing market. Firstly, the increasing demand for biopharmaceuticals, driven by aging populations and the prevalence of chronic diseases, is creating a burgeoning market for downstream processing solutions. Additionally, advancements in biotechnology and genetic engineering have led to the development of novel bioproducts, further fuelling the demand for efficient downstream processing technologies.

Moreover, stringent regulatory requirements for the approval of biopharmaceuticals and biotechnological products necessitate high-quality downstream processing to ensure product safety and efficacy. This has prompted biotech companies to invest in state-of-the-art downstream processing facilities and technologies.

Forecast Highlights on Global Downstream Processing Market

  • As per the forecast of Future Market Insights, the filters product type segment is slated to touch a value of nearly US$ 5,700 Million in the year 2022. This represents a robust CAGR during the assessment period of 2017-2022. The filters product type segment is estimated to account for more than one-fifth of the revenue share of the product type segment by the year 2017 and is forecasted to lose market share by 2022 over 2017.
  • As per the forecast of Future Market Insights, the contract manufacturing organizations segment will reach a value of nearly US$ 5,500 Million in the year 2017. This represents a robust CAGR growth during the forecast period. The contract manufacturing organizations segment is forecasted to account for more than one-third of the total revenue share of the end users segment by the end of the year 2017 and is expected to lose in market share by 2022 as compared with the year 2017.
  • As per the forecast of Future Market Insights, the monoclonal antibody production segment is slated to reach a value of about US$ 8,300 Million in 2022. The monoclonal antibody production segment is expected to gain market share by the end of the year 2022. The largest share is contributed by the North America region in the monoclonal antibody production segment.
  • Future Market Insights forecasts the gel chromatography segment to exhibit a compound annual growth rate (CAGR) of nearly 15.0% from 2017 to 2022.

Key Companies Profiled:

  • Thermo Fisher Scientific Inc.
  • GE Healthcare
  • Sartorius Stedim Biotech S.A.
  • Merck Millipore
  • Danaher Corporation
  • 3M Company
  • Boehringer Ingelheim
  • Lonza Group AG
  • Eppendorf AG
  • Finesse Solutions, Inc.
  • Bio-Rad Laboratories
  • Agilent technologies
  • Solida Biotech GmBH
  • Waters Corporation
  • Applikon BioTechnique/Getinge AB

Key Market Segments Covered In the Downstream Processing Industry Research:

By Product:

  • Chromatography Columns and Resins
  • Membrane Adsorbers
  • Single-use Products
  • Consumables and Accessories

By Technique:

  • Separation
  • Concentration
  • Purification

By Application:

  • Monoclonal Antibody Production
  • Vaccine Production
  • Insulin Production
  • Immunoglobulin Production
  • Erythropoietin Production
  • Other Application

By End User:

  • Biopharmaceutical Companies
  • CDMO/Contract Research Organization
  • Research/Academic Institutes

By Region:

  • North America
  • Latin America
  • Europe
  • South Asia
  • East Asia
  • Oceania
  • Middle East and Africa (MEA)