The Global Bone Cement & Glue Market is projected to reach USD 2,248 million by 2028 from USD 1,644 million in 2023, at a CAGR of 6.5% during the forecast period. The growth of this market is majorly driven by the Rising Demand for Minimally Invasive Surgeries with robotic assistance and Growing healthcare sector and Increasing Incidence of Orthopedic Conditions. However, Challenges associated with Variability of pathogen resistance may threat the growth of this market.

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Global Bone Cement & Glue Market Dynamics

DRIVER: Growing incidences of sports injuries

Globally, the incidence of sports injuries has increased over the last few years primarily due to the growing participation in sports as well as active participation in fitness activities (because of the growing focus on leading healthy lifestyles), Intensity and competitiveness, Insufficient recovery, and rest. Some of the major statistics in this regard have been mentioned below:

According to The Johns Hopkins University 2023, In the U.S., about 30 million children and teens participate in some form of organized sports, and more than 3.5 million injuries each year. Sports and recreational activities contribute to approximately 21% of all traumatic brain injuries among American children. Similarly, almost 50% of head injuries sustained in sports or recreational activities occur during bicycling, skateboarding, or skating incidents. More than 775,000 children, ages 14 and younger, are treated in hospital emergency rooms for sports-related injuries each year.

Restraints: High costs and extensive clinical data requirements for launching new bone cements

The development of bone cement is an extremely cost-intensive process. It takes significant investments in R&D to develop new products that effectively cater to market needs. The FDA approval process for surgical orthopedic cements is stringent and time-consuming, causing delays in bringing new bone cements to the market. The FDA demands more clinical data related to the safety and efficacy of the product, which results in tin additional R&D investments for companies. Despite the development of several advanced cements in the market, there is still a need for developing cost-effective bone cements with the appropriate clinical data required by regulatory authorities.

OPPORTUNITY: Rising awareness and demand for minimally invasive procedures

Minimally invasive surgeries offer benefits such as smaller incisions, reduced scarring, and faster recovery times. There is an increasing demand for minimally invasive orthopedic procedures, and bone cement and glue play a crucial role in these techniques. Opportunities exist for the development of specialized bone cement and glue products tailored for minimally invasive approaches. Minimally invasive procedures often result in reduced post-operative pain, shorter hospital stays, and faster rehabilitation compared to traditional open surgeries. This can lead to improved patient satisfaction and outcomes. The use of appropriate bone cement and glue products in these procedures contributes to the overall success and effectiveness of the treatment.

CHALLENGE: Product-related complications.

While bone cement and glue products are generally safe and effective, like any medical intervention, they can be associated with certain complications. Here are some potential complications associated with bone cement and glue:

• Infection: Infection is a possible complication following the use of bone cement and glue. Although efforts are made to maintain a sterile surgical environment, there is still a risk of bacterial contamination during the procedure or post-operatively. Infection can lead to implant loosening, prolonged healing, and the need for additional treatments or surgeries.
• Allergic reactions: Some individuals may experience allergic reactions to components of bone cement or glue, such as methacrylate monomers. Allergic reactions can manifest as localized inflammation, skin rashes, or more severe systemic reactions. Careful evaluation of patient history and selection of appropriate materials can help mitigate the risk of allergic reactions.
• Cement leakage: During the application of bone cement, there is a possibility of cement leakage into surrounding tissues or blood vessels. Cement leakage can lead to complications such as nerve impingement, embolism (if cement enters the bloodstream), or tissue damage. Proper surgical technique and monitoring can help reduce the risk of cement leakage.
• Implant loosening: Although bone cement is used to secure implants, there is still a possibility of implant loosening over time. Factors contributing to implant loosening include improper technique, poor bone quality, excessive weight-bearing, or inadequate cement fixation. Implant loosening may require revision surgery to address the instability and ensure long-term implant function.
• Adverse tissue reactions: Some individuals may experience adverse tissue reactions to bone cement or glue. These reactions can manifest as chronic inflammation, granuloma formation, or hypersensitivity reactions. The incidence of such reactions is relatively rare, but they can result in discomfort, implant failure, or the need for further interventions.
• Thermal necrosis: During the polymerization process of bone cement, heat is generated, which can potentially cause thermal necrosis (tissue damage due to excessive heat) in surrounding tissues. This risk is mitigated by proper cement handling, cooling techniques, and careful monitoring during the procedure.

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Based on Type, the Bone Glue market is segmented into Natural bone glue and Synthetic bone glue. The Natural bone glue segment is anticipated to have the highest shares during. The major factors contributing to the growth of this market are the potential advantages of natural bone glue include better biocompatibility, reduced risk of adverse reactions, and the ability to support tissue regeneration and healing. However, the development and commercialization of natural bone glue products have faced challenges such as standardization, and regulatory approvals.

Based on Loading, the Bone Cement & Glue market is segmented into Antibiotic-loaded bone cement, and non-Antibiotic-loaded bone cement. The Antibiotic-loaded bone cement segment is is anticipated to have the highest shares considering the applicatiobs as Antibiotic-loaded bone cement is also commonly used in revision surgeries, where there is a higher risk of infection due to the presence of existing implants, in addition, the effectiveness of antibiotic-loaded bone cement in reducing infection rates has been supported by clinical evidence and guidelines, making it a widely accepted and evidence-based practice. Likewise, Antibiotic-loaded bone cement maintains biocompatibility and bonding strength comparable to plain bone cement, making it a safe and effective option for surgical use.

US accounted for the largest share of the North American Bone cement & glue market in 2022.

Based on the region, the North American bone cement & glue market is segmented into US and Canada. In 2022, the US accounted for the largest share of the North American Bone cement & glue market. Growth in this market can be attributed to presence of stringent regulatory standard, rising healthcare expenditure, the increasing number of orthopedic surgical procedures performed in the US, the rising geriatric population, and the strong presence of bone cement & glue manufacturers.

India registered the highest growth rate in Asia Pacific Bone cement & glue market.

The APAC bone cement & glue market is segmented into Japan, China, India, and Rest of Apac. In 2022, India accounted for the highest growth rate of the Asian bone cement & glue market. The high growth rate of India can be attributed to the rising of a medical tourism in orthopedic surgery sector and the increasing geriatric population. An increase in the number of elderly people gives rise to various orthopedic and diseases which is highly susceptible to several procedures. Therefore, growth in this population segment will directly drive the demand for bone cement & glue products.

The Germany in European Bone cement & glue market to witness the second highest growth rate during the forecast period.

The Europe bone cement & glue market is segmented into Germany, France, the UK, and the Rest of Europe. Germany is registered the highest growth rate during the forecast period. The major factors contributing to the growth of this market are the high prevalence ofold age population, rising in sport related injuries, orthopedic cases, increasing R&D activities, strategic developments by key players.

Key Market Players:

Stryker (US), Zimmer Biomet (US) , Smith+Nephew.(UK), DePuy Synthes (a subsidiary of Johnson & Johnson - US) , Enovis (US) , Artivion, Inc (US), Cardinal Health. (US), Medtronic (Ireland), Globus Medical (US), and Heraeus Holding (Germany).

Recent Developments:

• In 2021, The company Smith & Nephew (UK) acquired the Extremity Orthopedics business of Integra LifeSciences to expand its shoulder, upper, and lower extremities product portfolio.
• In 2021, Zimmer Biomet (US) Completed the spinoff of spine and dental businesses into a new public company, ZimVie Inc. (“ZimVie”). The transaction was intended to benefit its stockholders by enhancing the focus of both Zimmer Biomet and ZimVie to meet the needs of patients and customers

Report Link: ( Bone Cement & Glue Market )

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