Age-related Macular Degeneration (AMD) is a progressive eye condition characterized by the deterioration of the macula, a small area in the center of the retina responsible for sharp, central vision. This degenerative process primarily affects individuals aged 50 and older, leading to a gradual loss of central vision and potentially severe visual impairment. AMD is categorized into two types: dry AMD, marked by the accumulation of drusen (yellow deposits) in the macula, and wet AMD, characterized by the growth of abnormal blood vessels beneath the macula, often resulting in leakage and scarring.

Because of rising awareness, an ageing population, and improvements in diagnostic and treatment technologies, the global market for age-related macular degeneration has grown significantly in recent years. To address the unmet medical needs of AMD patients, major players in the market are actively developing novel treatment approaches, such as gene therapies and anti-VEGF therapies. Research and development efforts targeting the exploration of possible biomarkers for early detection and customised treatment approaches are also on the rise in the market.

Global Age-related Macular Degeneration (AMD) report scope and segmentation.

Global Age-related Macular Degeneration (AMD) dynamics

The aging global population is a primary driver, as individuals aged 50 and above, who are more susceptible to AMD, constitute a growing demographic. Additionally, the increasing prevalence of lifestyle-related factors, such as poor diet and sedentary lifestyles, contributes to the rising incidence of AMD. Technological advancements in diagnostic tools, such as optical coherence tomography (OCT) and fundus imaging, enable early detection and monitoring, fostering market growth.

In terms of therapeutics, ongoing R&D initiatives to introduce cutting-edge treatment modalities are driving the market. Wet AMD management is dominated by anti-VEGF therapies, with new drug candidates being explored in ongoing clinical trials. The industry's dedication to expanding treatment options is demonstrated by the emergence of gene therapies, regenerative medicine, and combination therapies as viable paths forward. There are still issues, though, such as the high expense of medical care, the difficulty in accessing cutting-edge therapies, and the requirement for personalised medicine techniques. These elements give market participants the chance to investigate pricing tactics, broaden their consumer base, and work together on projects that improve patient accessibility and affordability. In general, the AMD market is defined by the dynamic interaction of changing demographics, advances in technology, and novel therapeutics, requiring industry participants to be flexible and strategically positioned.

Global Age-related Macular Degeneration (AMD) drivers

• Aging Population and Increased Incidence of AMD

The market for age-related macular degeneration (AMD) is heavily influenced by the growing number of people over 50 in the world. Given that age is the main risk factor for AMD, the number of elderly people in the population is growing, which adds to the condition's increased prevalence. The market is growing as a result of this shift in demographics, which increases demand for AMD diagnostics and treatments. The growing number of possible patients emphasises how crucial it is to carry out more research and development to meet the unique requirements of this elderly population.

• Technological Advancements in Diagnosis and Treatment

The market for AMD is largely driven by ongoing developments in diagnostic technologies, including fundus imaging and optical coherence tomography (OCT). These instruments facilitate prompt intervention by enabling early detection, precise diagnosis, and tracking of AMD progression. Furthermore, advancements in therapeutic approaches, specifically the triumph of anti-VEGF medications, have revolutionised the field of managing AMD. The emergence of regenerative medicine and gene therapies expands the range of available treatments and opens up new directions for individualised and focused care. The ongoing development of these technologies boosts AMD diagnosis and treatment efficacy and efficiency, which supports market growth.

Restraints:

• High Treatment Costs and Limited Accessibility

The market growth is severely limited by the high cost of AMD treatments, especially anti-VEGF therapies. There are differences in the availability of treatment due to the financial strain on patients and healthcare systems that restricts access to these cutting-edge therapies. For market participants, addressing the affordability issue is critical. To guarantee that more patients have access to state-of-the-art AMD treatments, strategic pricing models, partnerships, and advocacy initiatives are needed.

• Long-term Management Challenges

AMD requires ongoing care, including ongoing therapeutic interventions and routine monitoring. This creates problems for patient adherence and puts a burden on medical resources needed for ongoing treatment administration and follow-up. The intricacy of long-term care is increased by the frequent injections required by anti-VEGF treatments. To improve treatment adherence and lessen the burden on patients and healthcare systems, overcoming these obstacles requires creating more practical and patient-friendly treatment regimens in addition to innovations in sustained-release formulations.

Opportunities:

• Personalized Medicine and Targeted Therapies

The emerging field of personalized medicine offers a significant opportunity for the AMD market. As our understanding of the genetic and molecular basis of AMD expands, there is a growing potential for developing targeted therapies tailored to individual patient profiles. Precision medicine approaches can optimize treatment outcomes by considering genetic factors, biomarkers, and patient-specific characteristics, leading to more effective and personalized interventions for AMD.

Segment Overview

• By Type  

The market is classified into two primary types of AMD: Dry AMD and Wet AMD. Dry AMD is characterized by the gradual deterioration of light-sensitive cells in the macula, leading to a slow and progressive loss of central vision. On the other hand, Wet AMD involves the abnormal growth of blood vessels beneath the macula, leading to a more rapid and severe decline in vision. Both types present unique challenges in terms of diagnosis, treatment, and patient care, necessitating targeted approaches for each subtype.

• By End User

The end-user segment encompasses a diverse range of healthcare settings where AMD diagnosis and treatment take place. This includes Hospitals, where a comprehensive range of medical services are provided; Specialty Clinics, which focus specifically on ophthalmic care and AMD management; Ambulatory Surgical Centers, offering outpatient surgical procedures related to AMD; Home Healthcare, facilitating patient care within the comfort of their homes; and Others, representing various healthcare facilities involved in AMD management. Each end-user category plays a crucial role in delivering AMD-related services, emphasizing the need for tailored strategies to meet the specific requirements of each setting.

• By Distribution Channel

The distribution channel segment highlights the pathways through which AMD-related products and treatments reach end-users. Direct Tender involves procurement processes initiated by healthcare institutions to directly acquire medications and services. Retail Sales encompass over-the-counter purchases made by consumers seeking AMD-related products from pharmacies or other retail outlets. Efficient distribution channels are essential to ensure timely access to AMD treatments, and understanding the dynamics of these channels is vital for optimizing the reach and impact of AMD management solutions.

Global Age-related Macular Degeneration (AMD) Overview by Region

In North America, the market is characterized by a high prevalence of AMD cases, driven by an aging population and advanced diagnostic capabilities. The presence of well-established healthcare facilities, coupled with substantial investments in research and development, positions North America as a key player in the AMD market. Europe follows a similar trajectory, with a significant aging population contributing to a rising incidence of AMD. Access to advanced medical technologies and robust healthcare systems in Western European countries further amplifies the regional market's growth.

Asia-Pacific emerges as a dynamic market for AMD, driven by the increasing elderly population, changing lifestyle factors, and improving healthcare infrastructure. Rapid urbanization and lifestyle shifts contribute to the rising prevalence of AMD in countries like China and India. Additionally, the Asia-Pacific region witnesses a surge in healthcare awareness and adoption of advanced treatments, fostering market expansion. In contrast, Latin America and the Middle East & Africa regions face unique challenges, including limited access to healthcare services and lower awareness levels about AMD. However, growing efforts to enhance healthcare infrastructure and raise awareness about eye health are gradually influencing the market dynamics in these regions.

Global Age-related Macular Degeneration (AMD) market competitive landscape

Leading pharmaceutical companies such as Novartis, Roche, and Regeneron Pharmaceuticals play a pivotal role in driving innovation and dominating the AMD therapeutics sector. These companies focus on research and development activities to introduce novel drugs and therapies, often leveraging partnerships with academic institutions and smaller biotech firms to bolster their pipelines.

In addition to pharmaceutical giants, medical device manufacturers like Bausch + Lomb and Genentech contribute significantly to the competitive landscape, developing cutting-edge diagnostic tools and equipment for early AMD detection and precise monitoring. The competitive scenario is further enriched by the presence of specialized biotechnology firms, such as Ophthotech Corporation and Apellis Pharmaceuticals, dedicated to addressing specific challenges associated with AMD treatment. These companies often emphasize targeted therapeutic approaches, including gene therapies and complement inhibition, showcasing the industry's commitment to diversifying treatment modalities.

Global Age-related Macular Degeneration (AMD) Recent Developments

• Dec 2023, TruTag Technologies, Inc. and Spinnaker Biosciences, Inc. have recently formed a strategic supply partnership. This collaboration aims to leverage TruTag's advanced nano-porous silica (pSi) particles in the development and commercialization of Spinnaker's innovative therapy designed for treating age-related macular degeneration (AMD).
•  Aug 2023, Astellas Pharma Inc. led by President and CEO Naoki Okamura, announced today that the U.S. Food and Drug Administration (FDA) has granted approval for IZERVAY (avacincaptad pegol intravitreal solution) as a treatment for geographic atrophy (GA) secondary to age-related macular degeneration (AMD) on August 4, 2023. IZERVAY, a novel complement C5 inhibitor, stands out as the sole GA treatment endorsed by the FDA, demonstrating a statistically significant reduction (p<0.01) in the rate of GA progression at the 12-month primary endpoint across two Phase 3 clinical trials.

Scope of global Age-related Macular Degeneration (AMD) report

Global Age-related Macular Degeneration (AMD) report segmentation

Objectives of the Study

The objectives of the study are summarized in 5 stages. They are as mentioned below:

• Global Age-related Macular Degeneration (AMD) size and forecast:To identify and estimate the market size for global Age-related Macular Degeneration (AMD) market segmented by Type, By End-User, Distribution Channel and by region. Also, to understand the consumption/ demand created by consumers between 2024 and 2032.
• Market Landscape and Trends: To identify and infer the drivers, restraints, opportunities, and challenges for global Age-related Macular Degeneration (AMD)
• Market Influencing Factors: To find out the factors which are affecting the market of global Age-related Macular Degeneration (AMD) among consumers.
• Company Profiling: To provide a detailed insight into the major companies operating in the market. The profiling will include the financial health of the company's past 2-3 years with segmental and regional revenue breakup, product offering, recent developments, SWOT analysis, and key strategies.